How effective is lomustine for dogs? Lomustine is used as a first-line drug to treat cutaneous lymphoma of dogs with a response rate of 80 – 90% and 26% achieving complete remission. The duration of treatment to response is reported to be about three to four months. Lomustine is helpful for chemotherapy of mast cell tumors in both dogs and cats.
Does lomustine have side effects? Nausea, vomiting, loss of appetite, diarrhea, or mouth/lip sores may occur. Nausea and vomiting usually last for less than 24 hours and loss of appetite may last for several days. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting.
How long do chemo side effects last in dogs? In the majority of cases, the side effects are limited to no more than 24 to 48 hours. The white cell count is typically at its lowest point 7 to 10 days after treatment, and the cells naturally rebound quickly.
How quickly does lomustine work? Response rates and timing of the response. The patient typically starts to improve in about 3 to 5 days with some taking up to 2 weeks to show a response. About 80% of the patients respond to therapy when lymphoma or GME is suspected with lower response rates for brain tumors.